Technology Process of 4-(amino(phenyl)methyl)-N,N-dimethylaniline
There total 9 articles about 4-(amino(phenyl)methyl)-N,N-dimethylaniline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium azide; sulfuric acid;
In
chloroform;
at 40 - 80 ℃;
for 5.5h;
Schlenk technique;
Inert atmosphere;
DOI:10.1039/c5ob02418h
- Guidance literature:
-
With
hydrogenchloride; water;
In
ethanol;
at 25 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/ol802070d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iron(III) chloride; 1,10-Phenanthroline; sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate trihydrate / 1,2-dichloro-ethane / 8 h / 70 °C / Schlenk technique; Inert atmosphere; Glovebox
2: sodium hydroxide / water; methanol / 40 - 60 °C / Schlenk technique; Inert atmosphere
3: sulfuric acid; sodium azide / chloroform / 5.5 h / 40 - 80 °C / Schlenk technique; Inert atmosphere
With
iron(III) chloride; sodium azide; 1,10-Phenanthroline; sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate trihydrate; sulfuric acid; sodium hydroxide;
In
methanol; chloroform; water; 1,2-dichloro-ethane;
DOI:10.1039/c5ob02418h
