Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Base Information

Chemical Name:Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester
CAS No.:332097-76-4
Molecular Formula:C₁₉H₄₂O₅SSi₂
Molecular Weight:438.776
Hs Code.:

Synonyms:Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Suppliers and Price of Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

There total 4 articles about Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 332854-82-7
Methanesulfonic acid (3S,5S)-3,5-dihydroxy-cyclohexyl ester

: 332097-76-4
Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 22 ℃; for 24h;
DOI:10.1016/S0040-4020(00)01035-8

Reference yield:

: 131245-86-8
(1R,3R)-1,3-diacetoxy-5-hydroxy-cyclohexane

: 332097-76-4
Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / Et₃N / CH₂Cl₂ / 1 h / 0 °C

2: 100 percent / K₂CO₃ / methanol; H₂O / 5 h / 22 °C

3: 77 percent / imidazole / dimethylformamide / 24 h / 22 °C

With 1H-imidazole; potassium carbonate; triethylamine; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(00)01035-8

Reference yield:

: 13314-30-2
cis-1,3,5-cyclohexane-triol

: 332097-76-4
Methanesulfonic acid (3S,5S)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: pyridine / ethanol; H₂O / 4.75 h / 22 - 45 °C

1.2: 46.3 g / Lipase OF; aq. NaOH; sodium phosphate buffer / NaCl / cyclohexane / 21.5 h / 5 - 6 °C / pH 7.0

2.1: 100 percent / Et₃N / CH₂Cl₂ / 1 h / 0 °C

3.1: 100 percent / K₂CO₃ / methanol; H₂O / 5 h / 22 °C

4.1: 77 percent / imidazole / dimethylformamide / 24 h / 22 °C

With pyridine; 1H-imidazole; potassium carbonate; triethylamine; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(00)01035-8