8-Benzylaminoadenine

Base Information

• Chemical Name: 8-Benzylaminoadenine
• CAS No.: 127820-06-8
• Molecular Formula: C₁₂H₁₂N₆
• Molecular Weight: 240.267
• Mol file: 127820-06-8.mol

Synonyms:8-Benzylaminoadenine

Chemical Property of 8-Benzylaminoadenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-Benzylaminoadenine

There total 1 articles about 8-Benzylaminoadenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

8-bromoadenine (6974-78-3) + benzylamine (100-46-9) → 8-Benzylaminoadenine (127820-06-8)

Guidance literature:

at 150 ℃; for 2h;

DOI:10.1021/jm00170a005

Reference yield: 72.0%

C17H12ClF3N2O + 8-Benzylaminoadenine (127820-06-8) → 2-(6-amino-8-benzylaminopurin-9-ylmethyl)-3-(2-(trifluoromethyl)phenyl)-5-methyl-3H-quinazolin-4-one (1412898-10-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 0.0833333h; Microwave irradiation;

DOI:10.1016/j.tetlet.2012.08.137 DOI:10.1016/j.tetlet.2012.08.137

Reference yield:

8-Benzylaminoadenine (127820-06-8) → 8-Aminoadenine (28128-33-8)

Guidance literature:

With ammonia; sodium;

DOI:10.1021/jm00170a005

upstream raw materials:

8-bromoadenine

benzylamine

Downstream raw materials:

8-Aminoadenine

2-(6-amino-8-benzylaminopurin-9-ylmethyl)-3-(2-(trifluoromethyl)phenyl)-5-methyl-3H-quinazolin-4-one