4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride

Base Information

Chemical Name:4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride
CAS No.:78097-14-0
Molecular Formula:C₂₈H₄₂ClN₃O₄*ClH
Molecular Weight:556.573
Hs Code.:

Synonyms:4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride

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Chemical Property of 4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride

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Technology Process of 4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride

There total 2 articles about 4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.8%

: 39493-84-0
γ-morpholino-butyric acid hydrochloride

: 69982-17-8
4-[6-(2-chloro-4-methoxy-phenoxy)-hexyl]-3,5-diethyl-1H-pyrazole

: 78097-14-0
4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; for 120h; Ambient temperature;
DOI:10.1021/jm00138a018

Reference yield:

: 56219-57-9
4-[6-(2-chloro-4-methoxyphenoxy)hexyl]-3,5-heptanedione

: 78097-14-0
4-<6-(2-chloro-4-methoxyphenoxy)hexyl>-3,5-diethyl-1-<4-(4-morpholinyl)-1-oxobutyl>-1H-pyrazole hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 68.7 percent / hydrazine / ethanol / Heating

2: 37.8 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 120 h / Ambient temperature

With dicyclohexyl-carbodiimide; hydrazine; In ethanol; dichloromethane;
DOI:10.1021/jm00138a018