difluoro(4-chlorophenyl)-λ³-iodane

Base Information

• Chemical Name: difluoro(4-chlorophenyl)-λ³-iodane
• CAS No.: 350-45-8
• Molecular Formula: C₆H₄ClF₂I
• Molecular Weight: 276.452
• Mol file: 350-45-8.mol

Synonyms:difluoro(4-chlorophenyl)-λ³-iodane

Chemical Property of difluoro(4-chlorophenyl)-λ³-iodane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of difluoro(4-chlorophenyl)-λ³-iodane

There total 5 articles about difluoro(4-chlorophenyl)-λ³-iodane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

1-chloro-4-iodosylbenzene (52207-56-4) → difluoro(4-chlorophenyl)-λ3-iodane (350-45-8)

Guidance literature:

With hydrogen fluoride; In dichloromethane;

Reference yield:

1-Chloro-4-iodobenzene (637-87-6) → difluoro(4-chlorophenyl)-λ3-iodane (350-45-8)

Guidance literature:

With fluorine; In trichlorofluoromethane; Ambient temperature;

DOI:10.1016/S0022-1139(00)82593-2

Reference yield:

1-Chloro-4-iodobenzene (637-87-6) → difluoro(4-chlorophenyl)-λ3-iodane (350-45-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / Cl₂ / CH₂Cl₂ / 20 °C

2: 61 percent / aq. NaOH / tetrahydrofuran

3: 79 percent / aq. HF / CH₂Cl₂

With sodium hydroxide; hydrogen fluoride; chlorine; In tetrahydrofuran; dichloromethane;

upstream raw materials:

1-Chloro-4-iodobenzene

1-chloro-4-iodosylbenzene

4-chloro(dichloroiodo)benzene

Refernces

• 1、 Sawaguchi, Masanori,Ayuba, Shinichi,Hara, Shoji. "A practical synthetic method of iodoarene difluorides without fluorine gas and mercury salts". . p. 1802 - 1803. Retrieved 2007/10/03.
• 2、 Naumann, D.,Ruether, G.. "SYNTHESEN VON ARYLJOD(III)-DIFLUORIDEN DURCH DIREKTFLUORIERUNG VON ARYLJODIDEN". . p. 213 - 222. Retrieved 2007/10/02.