7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine

Base Information

Chemical Name:7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine
CAS No.:1404364-72-2
Molecular Formula:C₁₂H₁₆Cl₂IN₃OSi
Molecular Weight:444.175
Hs Code.:
Mol file:1404364-72-2.mol

Synonyms:2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine

Suppliers and Price of 7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+
10g
$ 266.00

Chemenu
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+
25g
$ 621.00

Chemenu
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+
100g
$ 1067.00

Arctom
2,4-Dichloro-5-iodo-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
1g
$ 50.00

Arctom
2,4-Dichloro-5-iodo-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
100g
$ 750.00

Arctom
2,4-Dichloro-5-iodo-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
25g
$ 350.00

Arctom
2,4-Dichloro-5-iodo-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
5g
$ 100.00

Arctom
2,4-Dichloro-5-iodo-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine ≥95%
10g
$ 150.00

AK Scientific
2,4-Dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine
1g
$ 127.00

ACHEMBLOCK
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 97%
5G
$ 90.00

Total 10 raw suppliers

Chemical Property of 7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine

Chemical Property:

PKA:1.14±0.30(Predicted)
Density:1.65±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine

There total 4 articles about 7-((2-(triMethylsilyl)ethoxy)Methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1012785-51-1
2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine

: 76513-69-4
(2-trimethylethylsilylethoxy)methyl chloride

: 1404364-72-2
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: 2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; With sodium hydride; In N,N-dimethyl-formamide; at -78 ℃; for 0.0833333h;

(2-trimethylethylsilylethoxy)methyl chloride; In N,N-dimethyl-formamide; at -78 - 20 ℃; for 1h;

Reference yield: 94.0%

: 442847-52-1
2,4-dichloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3 -d]pyrimidine

: 1404364-72-2
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: With N-iodo-succinimide; In N,N-dimethyl-formamide; at 80 ℃; for 6h;

Reference yield:

: 90213-66-4
2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine

: 1404364-72-2
2,4-dichloro-5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C

1.2: -78 - 20 °C

2.1: N-iodo-succinimide / N,N-dimethyl-formamide / 6 h / 80 °C

With N-iodo-succinimide; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide;