(Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Base Information

Chemical Name:(Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide
CAS No.:1390675-46-3
Molecular Formula:C₂₇H₂₅N₃O₅S₂
Molecular Weight:535.645
Hs Code.:

Synonyms:(Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Suppliers and Price of (Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

There total 3 articles about (Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1390675-63-4
C₂₀H₁₈N₂O₄S

: 70-55-3
toluene-4-sulfonamide

: 1390675-46-3
(Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2012.05.079

Reference yield:

: 1390675-52-1
C₁₂H₁₁NO₂S₂

: 1390675-46-3
(Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / ethanol / 7 h / 70 - 80 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane;
DOI:10.1016/j.bmc.2012.05.079

Reference yield:

: 135-02-4
ortho-anisaldehyde

: 1390675-46-3
(Z)-2-(5-(2-methoxybenzyliden)-4-oxo-4,5-dihydrothiazol-2-ylamino)-3-phenyl-N-tosylpropanamide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium acetate; acetic acid / 10 h / Reflux

2: N-ethyl-N,N-diisopropylamine / ethanol / 2.17 h / 20 °C

3: N-ethyl-N,N-diisopropylamine / ethanol / 7 h / 70 - 80 °C

4: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / 20 °C

With dmap; sodium acetate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; 1: Knoevenagel condensation;
DOI:10.1016/j.bmc.2012.05.079