3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Base Information

Chemical Name:3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid
CAS No.:129813-30-5
Molecular Formula:C₁₇H₁₇NO₄
Molecular Weight:299.326
Hs Code.:

Synonyms:3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Suppliers and Price of 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

There total 5 articles about 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 129833-16-5
3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid ethyl ester

: 129813-30-5
3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Guidance literature:: With hydrogenchloride; for 2h; Heating;
DOI:10.1021/jm00105a042

Reference yield:

: 129813-52-1
3-(2,5-dimethoxy-3,6-dimethylbenzyl)pyridine

: 129813-30-5
3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / TiCl₄ / CH₂Cl₂ / 4 h / Ambient temperature

2: 1.) NaH (60percent dispersion in mineral oil) / 1.) DMF, 0 deg C, 20 min, 2.) RT, 1 h

3: H₂ / 5percent Pd/C / acetic acid / 80 °C

4: 81 percent / cerium ammonium nitrate (CAN) / H₂O; acetonitrile / 1 h / 0 °C

5: 72 percent / concd. aq. HCl / 2 h / Heating

With hydrogenchloride; ammonium cerium(IV) nitrate; hydrogen; titanium tetrachloride; sodium hydride; palladium on activated charcoal; In dichloromethane; water; acetic acid; acetonitrile;
DOI:10.1021/jm00105a042

Reference yield:

: 129813-53-2
3-(4-formyl-2,5-dimethoxy-3,6-dimethylbenzyl)pyridine

: 129813-30-5
3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaH (60percent dispersion in mineral oil) / 1.) DMF, 0 deg C, 20 min, 2.) RT, 1 h

2: H₂ / 5percent Pd/C / acetic acid / 80 °C

3: 81 percent / cerium ammonium nitrate (CAN) / H₂O; acetonitrile / 1 h / 0 °C

4: 72 percent / concd. aq. HCl / 2 h / Heating

With hydrogenchloride; ammonium cerium(IV) nitrate; hydrogen; sodium hydride; palladium on activated charcoal; In water; acetic acid; acetonitrile;
DOI:10.1021/jm00105a042