5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Base Information

Chemical Name:5'-O-(4,4'-dimethoxytrityl)-8-azanebularine
CAS No.:771493-90-4
Molecular Formula:C₃₀H₂₉N₅O₆
Molecular Weight:555.59
Hs Code.:

Synonyms:5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Suppliers and Price of 5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

There total 4 articles about 5'-O-(4,4'-dimethoxytrityl)-8-azanebularine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 38874-46-3
8-azanebularine ribonucleoside

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 771493-90-4
5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Guidance literature:: With pyridine; silver nitrate; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/ja0472073

Reference yield:

: 92516-90-0
2',3',5'-tri-O-acetyl-8-azaadenosine

: 771493-90-4
5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Guidance literature:: Multi-step reaction with 4 steps

1: 60 percent / tBuONO; TMSBr / acetonitrile / 1 h / 0 °C

2: 80 percent / H₂; NaOAc / methanol / 8 h / 1900 Torr

3: 81 percent / methanolic NH₃ / 4 °C

4: 65 percent / pyridine; AgNO₃ / tetrahydrofuran / 20 °C

With pyridine; tert.-butylnitrite; trimethylsilyl bromide; ammonia; hydrogen; sodium acetate; silver nitrate; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/ja0472073

Reference yield:

: 92516-93-3
2',3',5'-tri-O-acetyl-8-azanebularine

: 771493-90-4
5'-O-(4,4'-dimethoxytrityl)-8-azanebularine

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / methanolic NH₃ / 4 °C

2: 65 percent / pyridine; AgNO₃ / tetrahydrofuran / 20 °C

With pyridine; ammonia; silver nitrate; In tetrahydrofuran;
DOI:10.1021/ja0472073