Technology Process of (5S)-5-[(4-methoxybenzyl)oxy-]6-heptenoic acid
There total 13 articles about (5S)-5-[(4-methoxybenzyl)oxy-]6-heptenoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene;
In
tetrahydrofuran; water; tert-butyl alcohol;
at 0 - 20 ℃;
for 3h;
DOI:10.1016/j.tet.2015.06.036
- Guidance literature:
-
With
lithium hydroxide monohydrate; water;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 4h;
DOI:10.2174/157017811794697502
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triphenylphosphine; 1H-imidazole; iodine / tetrahydrofuran / 0.17 h / 0 °C
2: sodium hydride / tetrahydrofuran / 4 h / 0 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C
4: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 4 h / 20 °C
5: sodium chlorite; 2-methyl-but-2-ene; sodium dihydrogenphosphate / tetrahydrofuran; tert-butyl alcohol; water / 3 h / 0 - 20 °C
With
1H-imidazole; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; tetrabutyl ammonium fluoride; iodine; sodium hydride; triphenylphosphine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; water; dimethyl sulfoxide; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2013.04.069
