2-Ethylpiperidine

Base Information

• Chemical Name: 2-Ethylpiperidine
• CAS No.: 1484-80-6
• Deprecated CAS: 78738-37-1
• Molecular Formula: C₇H₁₅N
• Molecular Weight: 113.203
• Hs Code.: 2933399990
• European Community (EC) Number: 216-058-7
• NSC Number: 211477
• UNII: Y4F771RRU8
• DSSTox Substance ID: DTXSID90883682
• Nikkaji Number: J114.019A
• Metabolomics Workbench ID: 68028
• ChEMBL ID: CHEMBL22270
• Mol file: 1484-80-6.mol

Synonyms:2-Ethylpiperidine;1484-80-6;Piperidine, 2-ethyl-;.alpha.-Ethylpiperidine;2-ETHYL-PIPERIDINE;2-ethyl piperidine;alpha-Ethylpiperidine;Y4F771RRU8;2-ethylpiperidin;EINECS 216-058-7;MFCD00005988;NSC 211477;NSC-211477;(+)-2-Ethyl-piperidine;bmse000714;C(C)C1CCCCN1;2-ETHYL-PIPERIDINE,;UNII-Y4F771RRU8;SCHEMBL30613;CHEMBL22270;DTXSID90883682;BAA48480;BBL100012;NSC211477;STL183254;AKOS000119095;AKOS016039385;LF-0519;SB47879;SB48000;E0308;FT-0612293;EN300-19079;AB01003590-01;F2190-0329

Chemical Property of 2-Ethylpiperidine

Chemical Property:

• Appearance/Colour: Clear colorless to yellow liquid
• Vapor Pressure: 5.45mmHg at 25°C
• Melting Point: -18 °C
• Refractive Index: n20/D 1.451(lit.)
• Boiling Point: 142.999 °C at 760 mmHg
• Flash Point: 33.755 °C
• PSA: 12.03000
• Density: 0.808 g/cm³
• LogP: 1.86730
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 113.120449483
• Heavy Atom Count: 8
• Complexity: 61.4

Purity/Quality:

97% ^*data from raw suppliers

2-Imidazol-1ylnicotinicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 10-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1CCCCN1

Technology Process of 2-Ethylpiperidine

There total 21 articles about 2-Ethylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-acetylpyridine (1122-62-9) → 2-ethylpiperidine (1484-80-6,78738-37-1)

Guidance literature:

With hydrogen; In n-heptane; at 150 ℃; for 72h; under 22502.3 Torr; chemoselective reaction; Catalytic behavior; Sealed tube;

DOI:10.1021/acs.inorgchem.1c03098

Reference yield: 81.0%

2-Ethylpyridine (100-71-0) → 2-ethylpiperidine (1484-80-6,78738-37-1)

Guidance literature:

With hydrogen; In n-heptane; at 150 ℃; for 72h; under 22502.3 Torr; chemoselective reaction; Catalytic behavior; Sealed tube;

DOI:10.1021/acs.inorgchem.1c03098

Reference yield:

piperidine (110-89-4) + carbon monoxide (201230-82-2) → 1-butyl-piperidine (4945-48-6) + N-methylcyclohexylamine (626-67-5) + 2-Methylpiperidin (109-05-7,3000-79-1) + 2-ethylpiperidine (1484-80-6,78738-37-1)

Guidance literature:

With hydrogen; iron catalyst; at 180 - 185 ℃; under 90007.2 Torr; Further byproducts given;

DOI:10.1007/BF00965446

upstream raw materials:

piperidine

ethene

di-tert-butyl peroxide

2-vinylpyridine

Downstream raw materials:

1-Methyl-2-ethyl-piperidin

2-(2-ethyl-piperidinomethyl)-4,5-dimethyl-phenol

3-(2-ethyl-piperidino)-1-(4-propoxy-phenyl)-propan-1-one

2-Ethyl-1-oxiranylmethyl-piperidine