diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate

Base Information

Chemical Name:diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate
CAS No.:1113027-27-2
Molecular Formula:C₃₈H₄₆ClN₆O₆P
Molecular Weight:749.247
Hs Code.:

diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate

Synonyms:diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate

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Chemical Property of diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate

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Technology Process of diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate

There total 1 articles about diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 1113027-21-6
diisopropyl (2,3-dideoxy-5-O-dimethoxytrityl-1-O-methanesulfonyl-3-aza-4a-carba-β-L-glycero-pentofuranos-3-yl)methylphosphonate

: 10310-21-1
2-amino-6-chloropurine

: 1113027-27-2
diisopropyl 1-(2-amino-6-chloropurin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethylphosphonate

Guidance literature:: 2-amino-6-chloropurine; With caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 0.333333h;

diisopropyl (2,3-dideoxy-5-O-dimethoxytrityl-1-O-methanesulfonyl-3-aza-4a-carba-β-L-glycero-pentofuranos-3-yl)methylphosphonate; In N,N-dimethyl-formamide; at 110 ℃; for 2h;
DOI:10.1016/j.tet.2008.11.035