2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Base Information

Chemical Name:2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal
CAS No.:155351-72-7
Molecular Formula:C₁₅H₂₂O₆
Molecular Weight:298.336
Hs Code.:

Synonyms:2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Suppliers and Price of 2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

There total 5 articles about 2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 155351-71-6
2-(benzyloxy)-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

: 155351-72-7
2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Guidance literature:: With palladium on activated charcoal; ammonium formate; In methanol; for 0.166667h; Ambient temperature;
DOI:10.1021/ja00082a023

Reference yield:

: 5034-74-2
5-bromo-3-methoxysalicylaldehyde

: 155351-72-7
2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Guidance literature:: Multi-step reaction with 5 steps

1: 87.8 percent / K₂CO₃ / ethanol / 3 h / Heating

2: 99.7 percent / TsOH*H₂O / benzene / 1 h / Heating

3: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 2.) THF, Et₂O, from -78 deg C to 0 deg C, 2 h

4: 99.5 percent / i-Pr₂NEt / CH₂Cl₂ / 15 h / Ambient temperature

5: 2.08 g / HCO₂NH₄, 10percent Pd/C / methanol / 0.17 h / Ambient temperature

With palladium on activated charcoal; n-butyllithium; ammonium formate; potassium carbonate; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; In methanol; ethanol; dichloromethane; benzene;
DOI:10.1021/ja00082a023

Reference yield:

: 155351-68-1
2-O-benzyl-5-bromo-2-hydroxy-3-methoxybenzaldehyde

: 155351-72-7
2-hydroxy-3-methoxy-5-<5-(methoxymethoxy)ethyl>benzaldehyde trimethylene acetal

Guidance literature:: Multi-step reaction with 4 steps

1: 99.7 percent / TsOH*H₂O / benzene / 1 h / Heating

2: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 2.) THF, Et₂O, from -78 deg C to 0 deg C, 2 h

3: 99.5 percent / i-Pr₂NEt / CH₂Cl₂ / 15 h / Ambient temperature

4: 2.08 g / HCO₂NH₄, 10percent Pd/C / methanol / 0.17 h / Ambient temperature

With palladium on activated charcoal; n-butyllithium; ammonium formate; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; benzene;
DOI:10.1021/ja00082a023