(S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Base Information

Chemical Name:(S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline
CAS No.:1380433-18-0
Molecular Formula:C₃₆H₃₁N₃O₃
Molecular Weight:553.66
Hs Code.:

Synonyms:(S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Suppliers and Price of (S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

There total 4 articles about (S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 908129-33-9
(S)-2-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)propanamide

: 31599-61-8
3,4-dimethyliodobenzene

: 1380433-18-0
(S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Guidance literature:: With silver(I) acetate; palladium diacetate; In toluene; at 60 ℃; for 62h;
DOI:10.1002/anie.201200731

Reference yield:

: 85-44-9
phthalic anhydride

: 1380433-18-0
(S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 2 h / 160 °C

2: N,N-dimethyl-formamide / toluene / 2 h / 80 °C

3: 2,6-dimethylpyridine / dichloromethane / 20 °C

4: silver(I) acetate; palladium diacetate / toluene / 62 h / 60 °C

With 2,6-dimethylpyridine; silver(I) acetate; palladium diacetate; N,N-dimethyl-formamide; In dichloromethane; toluene;
DOI:10.1002/anie.201200731

Reference yield:

: 4192-28-3
Phth-L-Ala-OH

: 1380433-18-0
(S)-N-(3,3-di(3,4-dimethylphenyl)-2-phthalimidopropionyl)-8-aminoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / toluene / 2 h / 80 °C

2: 2,6-dimethylpyridine / dichloromethane / 20 °C

3: silver(I) acetate; palladium diacetate / toluene / 62 h / 60 °C

With 2,6-dimethylpyridine; silver(I) acetate; palladium diacetate; N,N-dimethyl-formamide; In dichloromethane; toluene;
DOI:10.1002/anie.201200731