2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone

Base Information

Chemical Name:2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone
CAS No.:87356-71-6
Molecular Formula:C18H16N2O
Molecular Weight:276.3324
Hs Code.:
NSC Number:632909
DSSTox Substance ID:DTXSID601007499
Wikidata:Q83003540
ChEMBL ID:CHEMBL1964395

Synonyms:NSC632909;BRN 0803258;2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone;4(3H)-Pyrimidinone, 2-methyl-3-(2-methylphenyl)-6-phenyl-;5-24-03-00476 (Beilstein Handbook Reference);87356-71-6;2-methyl-3-(2-methylphenyl)-6-phenylpyrimidin-4(3h)-one;CHEMBL1964395;DTXSID601007499;NSC-632909;NCI60_010850;2-methyl-3-(o-tolyl)-6-phenyl-pyrimidin-4-one

Suppliers and Price of 2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone

Chemical Property:

Vapor Pressure:1.3E-07mmHg at 25°C
Boiling Point:430.4°C at 760 mmHg
Flash Point:214.1°C
Density:1.11g/cm³
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:276.126263138
Heavy Atom Count:21
Complexity:460

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CC=C1N2C(=NC(=CC2=O)C3=CC=CC=C3)C

Technology Process of 2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone

There total 6 articles about 2-Methyl-3-(2-methylphenyl)-6-phenyl-4(3H)-pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 35372-27-1
N'-o-tolyl-acetamidine

: 2216-94-6
phenylpropynoic acid ethyl ester

: 87356-71-6
2-methyl-6-phenyl-3-(o-tolyl)pyrimidin-4(3H)-one

Guidance literature:: In ethanol; at 80 ℃; for 96h;

Reference yield: 60.0%

: 57957-24-1
N-(1-phenylvinyl)acetamide

: 614-68-6
2-tolyl isocyanate

: 87356-71-6
2-methyl-6-phenyl-3-(o-tolyl)pyrimidin-4(3H)-one

Guidance literature:: With silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; mesitylenecarboxylic acid; In tetrahydrofuran; at 100 ℃; for 16h; Sealed tube; Inert atmosphere;
DOI:10.1039/c9cc03612a

Reference yield:

: 95-53-4
o-toluidine

: 87356-71-6
2-methyl-6-phenyl-3-(o-tolyl)pyrimidin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / AlCl₃

2: 61 percent / ethanol / 96 h / 80 °C

With aluminium trichloride; In ethanol;