N-o-tolylacetamidine

Base Information

• Chemical Name: N-o-tolylacetamidine
• CAS No.: 35372-27-1
• Molecular Formula: C₉H₁₂N₂
• Molecular Weight: 0
• Mol file: 35372-27-1.mol

Synonyms:N-o-tolylacetamidine

Chemical Property of N-o-tolylacetamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-o-tolylacetamidine

There total 4 articles about N-o-tolylacetamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

acetonitrile (75-05-8,26809-02-9) + o-toluidine (95-53-4) → N-(o-methylphenyl)acetamidine (35372-27-1)

Guidance literature:

With hydrogenchloride; for 4.5h; Heating;

DOI:10.1016/j.ejmech.2007.02.020

Reference yield: 45.0%

acetonitrile (75-05-8,26809-02-9) + o-toluidine (95-53-4) → N'-o-tolyl-acetamidine (35372-27-1)

Guidance literature:

With aluminium trichloride;

Reference yield: 42.0%

ortho-methylphenyl iodide (615-37-2) + acetamidine hydrochloride (124-42-5) → N'-o-tolyl-acetamidine (35372-27-1)

Guidance literature:

With copper(l) iodide; caesium carbonate; In acetonitrile; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo102235u

upstream raw materials:

acetonitrile

o-toluidine

ortho-methylphenyl iodide

acetamidine hydrochloride

Downstream raw materials:

2,6-dimethyl-3-o-tolyl-3H-pyrimidin-4-one

2-methyl-6-phenyl-3-(o-tolyl)pyrimidin-4(3H)-one

2,6-dimethyl-1-o-tolyl-1H-benzimidazole

1-(2-methylphenyl)-2-methyl-1H-imidazole-5-carbaldehyde