(4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Base Information

Chemical Name:(4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester
CAS No.:919769-67-8
Molecular Formula:C₂₃H₂₈O₈S
Molecular Weight:464.537
Hs Code.:

Synonyms:(4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Suppliers and Price of (4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

There total 7 articles about (4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 919769-66-7
3-[4,5-bis(benzyloxy)tetrahydropyran-2-yl]-3-hydroxypropionic acid methyl ester

: 124-63-0
methanesulfonyl chloride

: 919769-67-8
(4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/j.tetlet.2006.10.099

Reference yield:

: 252556-67-5
4(S)-[(2R)-1,4-Dioxaspiro[4.5]decanyl]-4-allyloxy-1-butene

: 919769-67-8
(4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 7 steps

1.1: 92 percent / [(Cy₃P)2Cl₂Ru=CHPh] / CH₂Cl₂ / 0.25 h / 20 °C

2.1: N-methylmorpholine N-oxide; OsO₄ / acetone; H₂O; 2-methyl-propan-2-ol / 2 h / 20 °C

3.1: NaH / dimethylsulfoxide / 0.25 h / 20 °C

3.2: 73 percent / dimethylsulfoxide / 12 h / 20 °C

4.1: 84 percent / HCl / methanol / 4 h / 20 °C

5.1: 78 percent / KBr; NaOCl; TEMPO / acetone; aq. NaHCO₃ / 1 h / 0 °C

6.1: 67 percent / tetrahydrofuran; diethyl ether / 0.17 h / 20 °C

7.1: 85 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

With pyridine; hydrogenchloride; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; osmium(VIII) oxide; sodium hydride; 4-methylmorpholine N-oxide; potassium bromide; Grubbs catalyst first generation; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; sodium hydrogencarbonate; dimethyl sulfoxide; acetone; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2006.10.099

Reference yield:

: 919769-60-1
2-(3,6-dihydro-2H-pyran-2-yl)-1,4-dioxaspiro[4.5]decane

: 919769-67-8
(4,5-bis-benzyloxy-tetrahydro-pyran-2-yl)-methanesulfonyloxy-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: N-methylmorpholine N-oxide; OsO₄ / acetone; H₂O; 2-methyl-propan-2-ol / 2 h / 20 °C

2.1: NaH / dimethylsulfoxide / 0.25 h / 20 °C

2.2: 73 percent / dimethylsulfoxide / 12 h / 20 °C

3.1: 84 percent / HCl / methanol / 4 h / 20 °C

4.1: 78 percent / KBr; NaOCl; TEMPO / acetone; aq. NaHCO₃ / 1 h / 0 °C

5.1: 67 percent / tetrahydrofuran; diethyl ether / 0.17 h / 20 °C

6.1: 85 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

With pyridine; hydrogenchloride; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; osmium(VIII) oxide; sodium hydride; 4-methylmorpholine N-oxide; potassium bromide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; sodium hydrogencarbonate; dimethyl sulfoxide; acetone; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2006.10.099