(R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

Base Information

Chemical Name:(R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester
CAS No.:438049-20-8
Molecular Formula:C₁₈H₂₆F₂N₂O₄
Molecular Weight:372.412
Hs Code.:

Synonyms:(R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

Suppliers and Price of (R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

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Technology Process of (R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

There total 7 articles about (R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 438050-32-9
(R)-2-ethyl-piperazine-1,4-dicarboxylic acid 4-tert-butyl ester 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

: 438049-20-8
(R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

Guidance literature:

Reference yield:

: 347195-55-5
(R)-1-benzyl-3-ethylpiperazine

: 438049-20-8
(R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

Guidance literature:: Multi-step reaction with 7 steps

1: hydrogenchloride / palladium / ethanol

2: triethylamine / methanol; dichloromethane

3: pyridine / dichloromethane

5: n-butyllithium; dihydrogen peroxide; acetic acid / tetrahydrofuran

With pyridine; hydrogenchloride; n-butyllithium; dihydrogen peroxide; acetic acid; triethylamine; palladium; In tetrahydrofuran; methanol; ethanol; dichloromethane;

Reference yield:

: 128427-05-4,438050-07-8
(R)-2-ethylpiperazine dihydrochloride

: 438049-20-8
(R)-2-ethyl-piperazine-1-carboxylic acid 1-[2,6-difluoro-3-(3-methoxy-propoxy)-benzyl]ester

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine / methanol; dichloromethane

2: pyridine / dichloromethane

4: n-butyllithium; dihydrogen peroxide; acetic acid / tetrahydrofuran

With pyridine; n-butyllithium; dihydrogen peroxide; acetic acid; triethylamine; In tetrahydrofuran; methanol; dichloromethane;