(S)-2-ETHYL-PIPERAZINE-2HCl

Base Information

• Chemical Name: (S)-2-ETHYL-PIPERAZINE-2HCl
• CAS No.: 128427-05-4
• Molecular Formula: C6H16Cl2N2
• Molecular Weight: 187.11064
• Hs Code.: 2933599590
• Mol file: 128427-05-4.mol

Synonyms:(S)-2-ETHYL-PIPERAZINE-2HCl

Chemical Property of (S)-2-ETHYL-PIPERAZINE-2HCl

Chemical Property:

• PSA: 24.06000
• LogP: 2.21940
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

(S)-2-ETHYLPIPERAZINE ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2-ETHYL-PIPERAZINE-2HCl

There total 5 articles about (S)-2-ETHYL-PIPERAZINE-2HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-1-benzyl-3-ethylpiperazine (347195-55-5) → (R)-2-ethylpiperazine dihydrochloride (128427-05-4,438050-07-8)

Guidance literature:

With hydrogenchloride; palladium; In ethanol;

Reference yield:

C6H11ClN2O2 → (R)-2-ethylpiperazine dihydrochloride (128427-05-4,438050-07-8)

Guidance literature:

C₆H₁₁ClN₂O₂; With borane-THF; In diethylene glycol dimethyl ether; for 18h; Heating / reflux;

With hydrogenchloride; In 1,4-dioxane; methanol; for 2h; Heating / reflux;

Reference yield:

(S)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester (325145-35-5) → 2-(S)-ethylpiperazine dihydrochloride (128427-05-4,438050-07-8)

Guidance literature:

With hydrogenchloride; In water; for 0.333333h;

upstream raw materials:

(R)-1-benzyl-3-ethylpiperazine

(R)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester

(S)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester

Downstream raw materials:

3-ethylpiperazine-1-carboxylic acid tert-butyl ester

tert-butyl (3R)-3-ethylpiperazine-1-carboxylate

Refernces

• 1、 -. "5,7-DIAMINOPYRAZOLO`4,3-D!PYRIMIDINES USEFUL IN THE TREATMENT OF HYPERTENSION". Page 213-214. . Retrieved 2008/06/13.
• 2、 -. "NOVEL SULFONYL DERIVATIVES". . . Retrieved 2008/06/13.