Diacyl chloride of benzene-1,4-dipropionic acid

Base Information

• Chemical Name: Diacyl chloride of benzene-1,4-dipropionic acid
• CAS No.: 46744-67-6
• Molecular Formula: C₁₂H₁₂Cl₂O₂
• Molecular Weight: 259.132
• Mol file: 46744-67-6.mol

Synonyms:Diacyl chloride of benzene-1,4-dipropionic acid

Chemical Property of Diacyl chloride of benzene-1,4-dipropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Diacyl chloride of benzene-1,4-dipropionic acid

There total 6 articles about Diacyl chloride of benzene-1,4-dipropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3'-(1,4-phenylene)dipropanoic acid (4251-21-2) → Diacyl chloride of benzene-1,4-dipropionic acid (46744-67-6)

Guidance literature:

With thionyl chloride;

Reference yield:

1,4-phenylenediacrylic acid (16323-43-6) → Diacyl chloride of benzene-1,4-dipropionic acid (46744-67-6)

Guidance literature:

Multi-step reaction with 5 steps

1: thionyl chloride / Reflux

2: toluene / Reflux

3: sodium tetrahydroborate; nickel(II) chloride hexahydrate / ethanol / 6 h

4: sodium hydroxide / ethanol / Reflux

5: thionyl chloride / Reflux

With sodium tetrahydroborate; thionyl chloride; nickel(II) chloride hexahydrate; sodium hydroxide; In ethanol; toluene;

DOI:10.1002/anie.201801462

Reference yield:

3-[4-(2-ethoxycarbonyl-ethyl)-phenyl]-propionic acid ethyl ester (70364-29-3) → Diacyl chloride of benzene-1,4-dipropionic acid (46744-67-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / Reflux

2: thionyl chloride / Reflux

With thionyl chloride; sodium hydroxide; In ethanol;

DOI:10.1002/anie.201801462

upstream raw materials:

3,3'-(1,4-phenylene)dipropanoic acid

3-[4-(2-ethoxycarbonyl-ethyl)-phenyl]-propionic acid ethyl ester

ethyl 3-(4-(2-ethoxycarbonylvinyl)phenyl)propenoate

1,4-phenylenediacrylic acid

Downstream raw materials:

α-5,15-<2.2'-<3,3'-(p-phenylene)dipropionamido>diphenyl>:ββ-10,20-bis(o-aminophenyl)porphyrin

α-5,15:β-10,20-bis<2,2'-<3,3'-(p-phenylene)dipropionamido>-diphenyl>porphyrin