ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote

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Chemical Name:ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote
CAS No.:540524-47-8
Molecular Formula:C₅₂H₅₄ClNO₃SSi
Molecular Weight:836.61
Hs Code.:

Synonyms:ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote

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Chemical Property of ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote

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Technology Process of ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote

There total 3 articles about ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: ethyl 3-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1H-indol-3-yl]ethyl}sulfanyl)propanoate

: 776-74-9
Bromodiphenylmethane

: 540524-47-8
ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote

Guidance literature:: ethyl 3-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1H-indol-3-yl]ethyl}sulfanyl)propanoate; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

Bromodiphenylmethane; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.5h;

Reference yield: 42.0%

: 540524-46-7
ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1H-indol-3-yl]ethyl}thio)phenyl]propanote

: 776-74-9
Bromodiphenylmethane

: 540524-47-8
ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1-(diphenylmethyl)-1H-indol-3-yl]ethyl}thio)phenyl]propanote

Guidance literature:: ethyl 3-[4-({2-[2-(2-{[tert-butyl(diphenyl)silyl]oxy}ethyl)-5-chloro-1H-indol-3-yl]ethyl}thio)phenyl]propanote; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

Bromodiphenylmethane; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;
DOI:10.1021/jm701467e