phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside

Base Information

• Chemical Name: phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside
• CAS No.: 196876-48-9
• Molecular Formula: C₂₅H₂₇NO₇S
• Molecular Weight: 485.558
• Mol file: 196876-48-9.mol

Synonyms:phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside

Chemical Property of phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside

There total 1 articles about phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + phenyl 3-O-benzyl-1-thio-β-D-galactopyranoside (196876-47-8) + cyanomethyl bromide (590-17-0) → phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside (196876-48-9)

Guidance literature:

Yield given. Multistep reaction; lp;

DOI:10.1016/S0008-6215(97)00142-0

Reference yield: 67.0%

phenyl 2,4-di-O-acetyl-3-O-benzyl-6-O-cyanomethyl-1-thio-β-D-galactopyranoside (196876-48-9) + octyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (196876-45-6) → Acetic acid (2S,3R,4S,5S,6R)-5-acetoxy-2-((2R,3S,4R,5R,6R)-5-acetylamino-4-benzyloxy-2-benzyloxymethyl-6-octyloxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-6-cyanomethoxymethyl-tetrahydro-pyran-3-yl ester (196876-53-6)

Guidance literature:

With 4 A molecular sieve; bromine; silver trifluoromethanesulfonate; In dichloromethane; at -30 ℃; for 1h;

DOI:10.1016/S0008-6215(97)00142-0

upstream raw materials:

acetic anhydride

phenyl 3-O-benzyl-1-thio-β-D-galactopyranoside

cyanomethyl bromide

Downstream raw materials:

Acetic acid (2S,3R,4S,5S,6R)-5-acetoxy-2-((2R,3S,4R,5R,6R)-5-acetylamino-4-benzyloxy-2-benzyloxymethyl-6-octyloxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-6-cyanomethoxymethyl-tetrahydro-pyran-3-yl ester