2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Base Information

Chemical Name:2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate
CAS No.:722538-56-9
Molecular Formula:C₃₃H₄₇NO₇S
Molecular Weight:601.805
Hs Code.:

Synonyms:2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Suppliers and Price of 2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

There total 6 articles about 2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 112-16-3
n-dodecanoyl chloride

: 722538-55-8
4-acetoxy-3-(4-methylphenylsulfonamido)-1-phenyl-(1R,3R)-butyl acetate

: 722538-56-9
2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1016/j.tet.2004.04.019

Reference yield:

: 51985-30-9,137845-37-5,144381-72-6
4-Methyl-N-[(E)-3-phenyl-prop-2-en-(E)-ylidene]-benzenesulfonamide

: 722538-56-9
2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Guidance literature:: Multi-step reaction with 8 steps

1.1: lithium diisopropylamide / tetrahydrofuran / 0.33 h / -78 °C

1.2: 61 percent / tetrahydrofuran / 0.33 h / -78 °C

2.1: 84 percent / N-bromosuccinimide; water / toluene; CHCl₃ / 1 h / 20 °C

3.1: 76 percent / tri-n-butyltin hydride; AIBN / benzene / 1.5 h / Heating

4.1: 96 percent / pyridine / CH₂Cl₂ / 4 h / 20 °C

5.1: 2,6-lutidine / acetonitrile / 0.08 h / 0 °C

6.1: 617 mg / K₂CO₃; NaBH₄ / acetonitrile; H₂O / 0.25 h / 0 - 20 °C

7.1: 97 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

8.1: 91 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 4 h / 20 °C

With pyridine; 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); water; tri-n-butyl-tin hydride; potassium carbonate; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; chloroform; water; toluene; acetonitrile; benzene; 5.1: Pummerer reaction;
DOI:10.1016/j.tet.2004.04.019

Reference yield:

: 70-55-3
toluene-4-sulfonamide

: 722538-56-9
2-(N-dodecanoyl-(4-methylphenyl)sulfonamido)-4-acetoxy-4-phenyl-(2R,4R)-butyl acetate

Guidance literature:: Multi-step reaction with 9 steps

1.1: 73 percent / BF₃*OEt₂ / benzene / 2 h / Heating

2.1: lithium diisopropylamide / tetrahydrofuran / 0.33 h / -78 °C

2.2: 61 percent / tetrahydrofuran / 0.33 h / -78 °C

3.1: 84 percent / N-bromosuccinimide; water / toluene; CHCl₃ / 1 h / 20 °C

4.1: 76 percent / tri-n-butyltin hydride; AIBN / benzene / 1.5 h / Heating

5.1: 96 percent / pyridine / CH₂Cl₂ / 4 h / 20 °C

6.1: 2,6-lutidine / acetonitrile / 0.08 h / 0 °C

7.1: 617 mg / K₂CO₃; NaBH₄ / acetonitrile; H₂O / 0.25 h / 0 - 20 °C

8.1: 97 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

9.1: 91 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 4 h / 20 °C

With pyridine; 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); boron trifluoride diethyl etherate; water; tri-n-butyl-tin hydride; potassium carbonate; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; chloroform; water; toluene; acetonitrile; benzene; 6.1: Pummerer reaction;
DOI:10.1016/j.tet.2004.04.019