Technology Process of (2R,3S)-4-(allyloxy)-3-(benzyloxy)-1,2-epoxybutane
There total 4 articles about (2R,3S)-4-(allyloxy)-3-(benzyloxy)-1,2-epoxybutane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; triphenylphosphine;
In
benzene;
1) 30 min at r.t., 2) 15 min at 140-145 deg C, 0.8 mmHg;
DOI:10.1021/jo00015a017
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) NaH / 1) DMF, 2) DMF, r.t.
2: Amberlite IR-120 resin, conc. HCl / ethanol; H2O / Ambient temperature
3: 79 percent / 1) triphenylphosphine, 2) diisopropyl azodicarboxylate / benzene / 1) 30 min at r.t., 2) 15 min at 140-145 deg C, 0.8 mmHg
With
hydrogenchloride; di-isopropyl azodicarboxylate; Amberlite IR-120 resin; sodium hydride; triphenylphosphine;
In
ethanol; water; benzene;
DOI:10.1021/jo00015a017
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) NaH / 1) DMF, 2) DMF, r.t.
2: Amberlite IR-120 resin, conc. HCl / ethanol; H2O / Ambient temperature
3: 79 percent / 1) triphenylphosphine, 2) diisopropyl azodicarboxylate / benzene / 1) 30 min at r.t., 2) 15 min at 140-145 deg C, 0.8 mmHg
With
hydrogenchloride; di-isopropyl azodicarboxylate; Amberlite IR-120 resin; sodium hydride; triphenylphosphine;
In
ethanol; water; benzene;
DOI:10.1021/jo00015a017
