(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal

Base Information

• Chemical Name: (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal
• CAS No.: 131755-79-8
• Molecular Formula: C₃₆H₅₆O₆Si
• Molecular Weight: 612.923
• Mol file: 131755-79-8.mol

Synonyms:(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal

Chemical Property of (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal

There total 9 articles about (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane-1-ol (131755-78-7) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal (131755-79-8)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; 1.) -80 degC, 10 min, 2.) -30 degC, 1 h;

DOI:10.1016/S0040-4020(01)85585-X

Reference yield:

mesitaldehyde dimethylacetal (64761-29-1) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal (131755-79-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 42 percent

2: 76 percent

3: 75 percent / 3N NaOH / ethanol / 4 h / Ambient temperature

4: 88 percent / oxalyl chloride, DMSO, Et₃N / CH₂Cl₂ / 1.) -80 degC, 10 min, 2.) -30 degC, 1 h

With sodium hydroxide; oxalyl dichloride; dimethyl sulfoxide; triethylamine; In ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)85585-X

Reference yield:

Benzoic acid (2R,3S,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester (114811-23-3) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonanal (131755-79-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 42 percent

2: 76 percent

3: 75 percent / 3N NaOH / ethanol / 4 h / Ambient temperature

4: 88 percent / oxalyl chloride, DMSO, Et₃N / CH₂Cl₂ / 1.) -80 degC, 10 min, 2.) -30 degC, 1 h

With sodium hydroxide; oxalyl dichloride; dimethyl sulfoxide; triethylamine; In ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)85585-X

upstream raw materials:

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane-1-ol

mesitaldehyde dimethylacetal

t-butyldimethylsiyl triflate

Benzoic acid (2R,3S,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester

Downstream raw materials:

(1EZ,3R,4S,5S,6R,7R,8R)-1-Benzoyloxy-7-<(1,1-dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)dec-1-ene

(3R,4S,5S,6R,7R,8R)-7-<(1,1-Dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)decanal

(3R,4S,5S,6R,7R,8R)-7-<(1,1-Dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)decan-1-ol

C₇₅H₁₀₆O₁₂SSi₂