C₅₇H₁₀₄FNO₆

Base Information

• Chemical Name: C₅₇H₁₀₄FNO₆
• CAS No.: 1402588-13-9
• Molecular Formula: C₅₇H₁₀₄FNO₆
• Molecular Weight: 918.454
• Mol file: 1402588-13-9.mol

Synonyms:C₅₇H₁₀₄FNO₆

Chemical Property of C₅₇H₁₀₄FNO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₅₇H₁₀₄FNO₆

There total 5 articles about C₅₇H₁₀₄FNO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C63H118FNO6Si (1402588-09-3) → C57H104FNO6 (1402588-13-9)

Guidance literature:

With 1H-imidazole; tetrabutyl ammonium fluoride; In tetrahydrofuran; at 22 ℃; for 5h;

DOI:10.1021/bc300266y

Reference yield:

C19H31FO2Si (1402587-96-5) → C57H104FNO6 (1402588-13-9)

Guidance literature:

Multi-step reaction with 5 steps

1: methyl vinyl ketone; sec.-butyllithium; copper(l) iodide / 1.5 h / -78 °C

2: sodium hydrogencarbonate / methanol / 25 °C

3: ammonium acetate; sodium cyanotrihydroborate / methanol / 48 h / 22 °C

4: triethylamine / dichloromethane / 72 h / 22 °C

5: tetrabutyl ammonium fluoride; 1H-imidazole / tetrahydrofuran / 5 h / 22 °C

With 1H-imidazole; copper(l) iodide; sodium cyanotrihydroborate; ammonium acetate; tetrabutyl ammonium fluoride; sec.-butyllithium; sodium hydrogencarbonate; methyl vinyl ketone; triethylamine; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1021/bc300266y

Reference yield:

1-(4-fluorophenyl)allyl alcohol (5724-03-8) → C57H104FNO6 (1402588-13-9)

Guidance literature:

Multi-step reaction with 6 steps

1: sodium hydride / N,N-dimethyl-formamide / 15 h / 22 °C

2: methyl vinyl ketone; sec.-butyllithium; copper(l) iodide / 1.5 h / -78 °C

3: sodium hydrogencarbonate / methanol / 25 °C

4: ammonium acetate; sodium cyanotrihydroborate / methanol / 48 h / 22 °C

5: triethylamine / dichloromethane / 72 h / 22 °C

6: tetrabutyl ammonium fluoride; 1H-imidazole / tetrahydrofuran / 5 h / 22 °C

With 1H-imidazole; copper(l) iodide; sodium cyanotrihydroborate; ammonium acetate; tetrabutyl ammonium fluoride; sec.-butyllithium; sodium hydride; sodium hydrogencarbonate; methyl vinyl ketone; triethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; 1: |Williamson Ether Synthesis;

DOI:10.1021/bc300266y

upstream raw materials:

C₁₉H₃₁FO₂Si

C₆₃H₁₁₈FNO₆Si

4-fluorobenzaldehyde

1-(4-fluorophenyl)allyl alcohol