5724-03-8

Basic information

• Product Name: Benzenemethanol, a-ethenyl-4-fluoro-
• Synonyms: 1-(4-fluorophenyl)allyl alcohol;p-(4-fluorophenyl)prop-2-en-1-ol;(+/-)-1-(4'-fluorophenyl)prop-2-en-1-ol;1-(4-fluorophenyl)-2-propen-1-ol
• CAS NO: 5724-03-8
• Molecular Formula: C9H9FO
• Molecular Weight: 152.168
• Mol File: 5724-03-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 224.6±25.0 °C(Predicted)
• Density: 1.116±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanol, a-ethenyl-4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-ethenyl-4-fluoro-(5724-03-8)
• EPA Substance Registry System: Benzenemethanol, a-ethenyl-4-fluoro-(5724-03-8)

Safety Data

• Hazardous Substances Data: 5724-03-8(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 3536-96-7 vinylmagnesium chloride 
• 107-02-8 acrolein 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 1826-67-1 vinyl magnesium bromide 
• 352-13-6 4-flourophenylmagnesium bromide 

Downstream Products

• 124980-95-6 3-(4-fluorophenyl)prop-2-en-1-ol 
• 861395-19-9 1-acetoxy-1-(4-fluorophenyl)-2-propylene 
• 124980-95-6 (E)-3-(4-fluorophenyl)-2-propen-1-ol 
• 1073277-35-6 (+/-)-1-(4'-fluorophenyl)prop-2-en-1-yl tert-butyl carbonate 
• 456-03-1 1-(4-fluorophenyl)propan-1-one 
• 701-47-3 1-(4-fluorophenyl)propanol 
• 1357567-42-0 (Z)-methyl 3-bromo-2-(3-(4-fluorophenyl)-3-oxopropyl)oct-2-enoate 
• 56201-96-8 1-(4-fluorophenyl)-3-(4-methylphenyl)-1-propenone 
• 24654-55-5 trans-4-fluorocinnamaldehyde 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

Size-Exclusion Borane-Catalyzed Domino 1,3-Allylic/Reductive Ireland–Claisen Rearrangements: Impact of the Electronic and Structural Parameters on the 1,3-Allylic Shift Aptitude

The reductive Ireland–Claisen rearrangement through borane-mediated hydrosilylation is reported. The method employs a borane catalyst with a special structural design and affords access to synthetically relevant products with high diastereoselectivity. Depending on electronic and structural parameters, the reaction can be coupled with a 1,3-allylic shift, thus the valence isomer of the Ireland–Claisen product is formed.

Enantioselective addition of selenosulfonates to α,β-unsaturated ketones

An organo-catalyzed enantioselective addition of selenosulfonates to α,β-unsaturated ketones was developed for the first time. With a chiral squaramide as an efficient catalyst, the desired α-selenylated ketones were obtained in a good yields with high enantioselectivity up to 89% ee, and good results could be obtained on a gram scale. The products could also be efficiently transformed into useful building blocks with a propenylic stereocenter; the strategy presented in this study may find further applications in organic synthesis.

1,4-Diazabicyclo[2.2.2]octane-Promoted Aminotrifluoromethylthiolation of α,β-Unsaturated Carbonyl Compounds: N-Trifluoromethylthio-4-nitrophthalimide Acts as Both the Nitrogen and SCF3 Sources

A novel difunctionalization reaction is described. It uses N-trifluoromethylthio-4-nitrophthalimide as the reagent, which serves as both the nitrogen and SCF3 sources. In the presence of DABCO (1,4-diazabicyclo[2.2.2]octane), the nitrogen and SCF3 groups can be incorporated into α,β-unsaturated carbonyl compounds easily and give versatile β-amino ketones and esters in good yields. This difunctionalization reaction features mild reaction conditions, high atom-economy, and efficient access to α-SCF3 amino acids.