(Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

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Chemical Name:(Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate
CAS No.:1246022-19-4
Molecular Formula:C₂₃H₃₁BrN₂O₂
Molecular Weight:447.415
Hs Code.:

Synonyms:(Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

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Technology Process of (Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

There total 1 articles about (Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1246022-17-2
2-(2-bromo-1H-pyrrol-3-yl)aniline

: 1246022-15-0
(E)-tert-butyl 4-ethylidene-7-iodoheptanoate

: 1246022-19-4
(Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

Guidance literature:: 2-(2-bromo-1H-pyrrol-3-yl)aniline; With potassium hexamethylsilazane; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

(E)-tert-butyl 4-ethylidene-7-iodoheptanoate; In tetrahydrofuran; at -78 - 25 ℃; Inert atmosphere;
DOI:10.1021/ol101523z

Reference yield: 87.0%

: 1246022-19-4
(Z)-tert-butyl 7-(3-(2-aminophenyl)-2-bromo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

: 1246022-20-7
(Z)-tert-butyl 7-(3-(2-aminophenyl)-2-iodo-1H-pyrrol-1-yl)-4-ethyleneheptanoate

Guidance literature:: With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine; In 1,4-dioxane; at 110 ℃; for 24h; Inert atmosphere; sealed tube;
DOI:10.1021/ol101523z