5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

Base Information

• Chemical Name: 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide
• CAS No.: 247566-80-9
• Molecular Formula: C₂₁H₂₁N₃O₆
• Molecular Weight: 411.414
• Mol file: 247566-80-9.mol

Synonyms:5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

Chemical Property of 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide

There total 84 articles about 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Cyanobenzyl alcohol (874-89-5) → 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247566-80-9)

Guidance literature:

Multi-step reaction with 6 steps

3: hydrazine hydrate / ethanol

5: pyridine

6: silica gel / dichloromethane; acetonitrile

With hydrazine hydrate; silica gel; In pyridine; ethanol; dichloromethane; acetonitrile;

Reference yield:

tetrapropylammonium perruthennate (114615-82-6) + 2-(trans-4-hydroxycyclohexylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide + 4-methylmorpholine N-oxide (7529-22-8) → 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247566-80-9)

Guidance literature:

silica gel; In dichloromethane; acetonitrile;

Reference yield:

ethyl 3-methoxy-4-(2-methoxyethoxy)benzoate (196194-41-9) → 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247566-80-9)

Guidance literature:

Multi-step reaction with 7 steps

2: N-methyl-acetamide; dichloromethane

3: trichlorophosphate / pyridine

4: tetrahydrofuran; ethyl acetate

6: pyridine

7: silica gel / dichloromethane; acetonitrile

With trichlorophosphate; silica gel; In tetrahydrofuran; pyridine; N-methyl-acetamide; dichloromethane; ethyl acetate; acetonitrile;

upstream raw materials:

tetrapropylammonium perruthennate

4-methylmorpholine N-oxide

3-methoxy-4-(2-methoxyethoxy)benzonitrile

2-(cyclopentylamino)-5-nitrobenzoic acid