2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

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Chemical Name:2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester
CAS No.:1251933-17-1
Molecular Formula:C₂₁H₁₉ClN₄O₄
Molecular Weight:426.859
Hs Code.:

Synonyms:2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

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Chemical Property of 2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

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Technology Process of 2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

There total 1 articles about 2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1668-10-6
glycinamide hydrochloride

: 308845-81-0
2-(3,5-dichloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

: 1251933-17-1
2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 100 ℃; for 2.5h; Microwave irradiation; Sealed vial;
DOI:10.1016/j.bmc.2010.06.101

Reference yield:

: 1251933-17-1
2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester

: 1251933-95-5
C₁₄H₁₃ClN₄O₄

Guidance literature:: 2-(3-(2-amino-2-oxoethylamino)-5-chloro-2-oxo-6-phenylpyrazin-1(2H)-yl)acetic acid benzyl ester; With water; potassium carbonate; In acetonitrile; at 120 ℃; for 0.75h; Microwave irradiation; Sealed vial;

With hydrogenchloride; In water; ethyl acetate; pH=2;
DOI:10.1016/j.bmc.2010.06.101