O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Base Information

Chemical Name:O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate
CAS No.:457645-32-8
Molecular Formula:C₂₆H₄₀O₇SSi
Molecular Weight:524.751
Hs Code.:

O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Synonyms:O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Suppliers and Price of O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

There total 7 articles about O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1005-56-7
phenylcarbonochloridothioate

: 457645-31-7
(3aS,4R,5R,5aS,9aR,9bS)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,8,8-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-5-ol

: 457645-32-8
O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Guidance literature:: With pyridine;
DOI:10.1055/s-2002-31900

Reference yield:

: 221044-99-1
(3aS,4R,5aR,9aR,9bS)-5-benzylidene-2,2,8,8-tetra-methylhexahydro-3aH-[1,3]dioxolo[4,5-h][1,3]benzodioxin-4-yl tert-butyl(dimethyl)silyl ether

: 457645-32-8
O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: O₃ / methanol; CH₂Cl₂ / -78 °C

1.2: Me₂S / methanol; CH₂Cl₂ / 3 h / -78 - 20 °C

2.1: 210 mg / CeCl₃*H₂O; NaBH₄ / methanol / 0 - 20 °C

3.1: 70 percent / pyridine / acetonitrile / 1 h / 85 °C

With pyridine; sodium tetrahydroborate; cerium(III) chloride; ozone; In methanol; dichloromethane; acetonitrile;
DOI:10.1016/S0957-4166(03)00532-9

Reference yield:

: 221044-98-0
1-phenyl-1,2-dideoxy-7-O-(phenoxythiocrbonyl)-4,5:6,8-di-O-isopropylidene-3-O-(tert-butyldimethylsilyl)-D-talo-D-glycero-oct-1-yne

: 457645-32-8
O-(3aS,4R,4aR,8aS,9R,9aR)-4-{[tert-butyl(dimethyl)silyl]oxy}-2,2,6,6-tetramethylhexahydro-3aH-[1,3]-dioxolo[4,5-h][1,3]benzodioxin-9-yl-O-phenyl thiocarbonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: 38 percent / HBu₃Sn; AIBN / toluene / 12 h / 85 °C

2.1: O₃ / methanol; CH₂Cl₂ / -78 °C

2.2: Me₂S / methanol; CH₂Cl₂ / 3 h / -78 - 20 °C

3.1: 210 mg / CeCl₃*H₂O; NaBH₄ / methanol / 0 - 20 °C

4.1: 70 percent / pyridine / acetonitrile / 1 h / 85 °C

With pyridine; sodium tetrahydroborate; cerium(III) chloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; ozone; In methanol; dichloromethane; toluene; acetonitrile;
DOI:10.1016/S0957-4166(03)00532-9