Clitidine

Base Information

Chemical Name:Clitidine
CAS No.:63592-84-7
Molecular Formula:C11H14N2O6
Molecular Weight:270.2387
Hs Code.:
DSSTox Substance ID:DTXSID50979813
Nikkaji Number:J18.741K
Wikidata:Q105004436,Q82965538

Synonyms:Clitidine;Chrytidine;63592-84-7;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-iminopyridine-3-carboxylic acid;DTXSID50979813;CHEBI:133925;C19977;4-Imino-1-pentofuranosyl-1,4-dihydropyridine-3-carboxylic acid;4-imino-1-beta-ribofuranosyl-1,4-dihydro-3-pyridinecarboxylic acid

Suppliers and Price of Clitidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Clitidine

Chemical Property:

Vapor Pressure:2.36E-14mmHg at 25°C
Boiling Point:549.3°C at 760 mmHg
Flash Point:286°C
PSA：136.00000
Density:1.76g/cm³
LogP:-1.62300
XLogP3:-1.4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:270.08518617
Heavy Atom Count:19
Complexity:460

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN(C=C(C1=N)C(=O)O)C2C(C(C(O2)CO)O)O
Isomeric SMILES:C1=CN(C=C(C1=N)C(=O)O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

Technology Process of Clitidine

There total 8 articles about Clitidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 63592-87-0
3-methoxycarbonyl-4-imino-1-(3,5-di-O-benzoyl-β-D-ribofuranosyl)-1,4-dihydropyridine hydrochloride

: 63592-84-7
clitidine

Guidance literature:: With triethylamine; In methanol; water; Ambient temperature;
DOI:10.1016/0040-4020(82)80107-5

Reference yield:

: 16135-36-7
methyl 4-aminonicotinate

: 63592-84-7
clitidine

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / CH₂Cl₂ / Ambient temperature

2: 89 percent / Et₃N / methanol; H₂O / Ambient temperature

With triethylamine; In methanol; dichloromethane; water;
DOI:10.1016/0040-4020(82)80107-5

Reference yield:

: 63592-86-9
3,5-di-O-benzoyl-D-ribofuranosyl chloride

: 63592-84-7
clitidine

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / CH₂Cl₂ / Ambient temperature

2: 89 percent / Et₃N / methanol; H₂O / Ambient temperature

With triethylamine; In methanol; dichloromethane; water;
DOI:10.1016/0040-4020(82)80107-5