4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Base Information

Chemical Name:4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate
CAS No.:565452-46-2
Molecular Formula:C₂₈H₄₁F₃O₄SSi
Molecular Weight:558.778
Hs Code.:

Synonyms:4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Suppliers and Price of 4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

There total 8 articles about 4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 565452-45-1
4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenol

: 565452-46-2
4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Guidance literature:: With pyridine; In dichloromethane; for 4h;
DOI:10.1021/jm0301181

Reference yield:

: 13154-24-0
triisopropylsilyl chloride

: 565452-46-2
4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: 72 percent / imidazole / 1,2-dichloro-ethane / Heating

2.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -78 °C

2.2: 77 percent / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.1: 100 percent / H₂ / Pd/C / ethyl acetate; ethanol / 24 h / 1810.02 Torr

4.1: 99 percent / pyridine / CH₂Cl₂ / 4 h

With pyridine; 1H-imidazole; n-butyllithium; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1021/jm0301181

Reference yield:

: 7463-51-6
4-bromo-3,5-dimethylphenol

: 565452-46-2
4-[3-isopropyl-4-(triisopropylsilyloxy)benzyl]-3,5-dimethylphenyltrifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 78 percent / K₂CO₃ / dimethylformamide / 20 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -78 °C

2.2: 80 percent / tetrahydrofuran; hexane / 0.33 h / -78 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -78 °C

3.2: 77 percent / tetrahydrofuran; hexane / 0.5 h / -78 °C

4.1: 100 percent / H₂ / Pd/C / ethyl acetate; ethanol / 24 h / 1810.02 Torr

5.1: 99 percent / pyridine / CH₂Cl₂ / 4 h

With pyridine; n-butyllithium; hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm0301181