3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Base Information

• Chemical Name: 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride
• CAS No.: 1202780-14-0
• Molecular Formula: C₂₇H₂₈ClN₅O₄S*ClH
• Molecular Weight: 590.53

Synonyms:3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Chemical Property of 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

There total 1 articles about 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4-(5-{5-[(3-chlorophenyl)methylsulfonyl]-2-oxodihydroindol-3-ylidenemethyl}-2,4-dimethyl-1H-pyrrole-3-carbonyl)piperazine-1-carboxylic acid tert-butyl ester (1202780-13-9) → 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride (1202780-14-0)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; Cooling with ice;

DOI:10.1021/jm900803q

Reference yield:

[11C]methyl iodide (54245-42-0) + 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride (1202780-14-0) → 3-[3,5-dimethyl-4-(4-[(11)C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride (1202854-09-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 0.166667h;

DOI:10.1021/jm900803q

upstream raw materials:

4-(5-{5-[(3-chlorophenyl)methylsulfonyl]-2-oxodihydroindol-3-ylidenemethyl}-2,4-dimethyl-1H-pyrrole-3-carbonyl)piperazine-1-carboxylic acid tert-butyl ester

Downstream raw materials:

3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1202780-14-0 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send