3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine

Base Information

• Chemical Name: 3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine
• CAS No.: 1434133-35-3
• Molecular Formula: C₂₆H₃₁NO₅
• Molecular Weight: 437.536
• Mol file: 1434133-35-3.mol

Synonyms:3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine

Chemical Property of 3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine

There total 2 articles about 3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.1%

1-propyl-4-piperidone (23133-37-1) + 3,4-dimethoxy-benzaldehyde (120-14-9) → 3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine (1434133-35-3)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 5 - 8 ℃;

DOI:10.1016/j.bmc.2013.03.057

Reference yield: 58.6%

(3E,5E)-3,5-bis(3,4-dimethoxybenzylidene)piperidin-4-one + propan-1-ol (71-23-8) → 3,5-bis((E)-3,4-dimethoxybenzylidene)-4-methylene-1-propylpiperidine (1434133-35-3)

Guidance literature:

(3E,5E)-3,5-bis(3,4-dimethoxybenzylidene)piperidin-4-one; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.5h;

propan-1-ol; In tetrahydrofuran; mineral oil;

DOI:10.1016/j.ejmech.2018.03.051

upstream raw materials:

1-propyl-4-piperidone

3,4-dimethoxy-benzaldehyde

propan-1-ol