Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis-

Base Information

Chemical Name:Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis-
CAS No.:126810-22-8
Molecular Formula:C₁₈H₂₈N₂O₂*ClH
Molecular Weight:340.893
Hs Code.:
DSSTox Substance ID:DTXSID50155296
Mol file:126810-22-8.mol

Synonyms:Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis-;126810-22-8;cis-N-(1-(2-Ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenylacetamide monohydrochloride;LS-9499;DTXSID50155296

Suppliers and Price of Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis-

Chemical Property:

Vapor Pressure:1.02E-06mmHg at 25°C
Boiling Point:403.5°C at 760 mmHg
Flash Point:197.8°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:340.1917559
Heavy Atom Count:23
Complexity:342

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOCCN1CCC(C(C1)C)N(C2=CC=CC=C2)C(=O)C.Cl
Isomeric SMILES:CCOCCN1CC[C@H]([C@H](C1)C)N(C2=CC=CC=C2)C(=O)C.Cl

Technology Process of Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis-

There total 8 articles about Acetamide, N-(1-(2-ethoxyethyl)-3-methyl-4-piperidinyl)-N-phenyl-, monohydrochloride, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

: 125080-82-2,125080-86-6
1-(2-ethoxyethyl)-3a-methyl-4e-(phenylamino)piperidine

: 75-36-5
acetyl chloride

: 126810-22-8,126810-23-9
1-(2-ethoxyethyl)-3a-methyl-4e-(phenylacetamido)piperidine hydrochloride

Guidance literature:: In benzene; for 24h; Ambient temperature;
DOI:10.1007/BF00764437

Reference yield: 80.4%

: 125080-82-2,125080-86-6
1-(2-ethoxyethyl)-3e-methyl-4e-(phenylamino)piperidine

: 75-36-5
acetyl chloride

: 126810-22-8,126810-23-9
1-(2-ethoxyethyl)-3e-methyl-4e-(phenylacetamido)piperidine hydrochloride

Guidance literature:: In benzene; for 24h; Ambient temperature;
DOI:10.1007/BF00764437

Reference yield:

: 104192-39-4
1-(2-ethoxyethyl)-3-methyl-4-ketopiperidine

: 126810-22-8,126810-23-9
1-(2-ethoxyethyl)-3e-methyl-4e-(phenylacetamido)piperidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 55.36 percent / p-toluenesulfonic acid / benzene / 40 h / Heating

2: NaBH₄ / ethanol / 11 h / Ambient temperature

3: 80.4 percent / benzene / 24 h / Ambient temperature

With sodium tetrahydroborate; toluene-4-sulfonic acid; In ethanol; benzene;
DOI:10.1007/BF00764437