N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Base Information

Chemical Name:N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide
CAS No.:78734-33-5
Molecular Formula:C₄₆H₄₄N₄O₁₀
Molecular Weight:812.876
Hs Code.:

Synonyms:N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Suppliers and Price of N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

There total 3 articles about N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.1%

: 20662-53-7
4-(2-keto-1-benzimidazolinyl)piperidine

: 61406-62-0
N,O,O'-tribenzyloxycarbonyl-methyldopa

: 78734-33-5
N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 5h;
DOI:10.1248/cpb.30.474

Reference yield:

: 555-30-6,555-29-3,88620-56-8
3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine

: 78734-33-5
N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Guidance literature:: Multi-step reaction with 2 steps

1: 36.3 percent / NaOH / H₂O; diethyl ether / 3 h / 0 °C

2: 62.1 percent / DCC / CH₂Cl₂ / 5 h / 0 °C

With sodium hydroxide; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane; water;
DOI:10.1248/cpb.30.474

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 78734-33-5
N-benzyloxycarbonyl-3,4-dibenzyloxycarbonyloxyphenyl-2-methyl-L-alanine<4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)>piperidinamide

Guidance literature:: Multi-step reaction with 2 steps

1: 36.3 percent / NaOH / H₂O; diethyl ether / 3 h / 0 °C

2: 62.1 percent / DCC / CH₂Cl₂ / 5 h / 0 °C

With sodium hydroxide; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane; water;
DOI:10.1248/cpb.30.474