2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Base Information

Chemical Name:2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside
CAS No.:174149-28-1
Molecular Formula:C₄₀H₄₄O₁₀Si
Molecular Weight:712.869
Hs Code.:

Synonyms:2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Suppliers and Price of 2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

There total 9 articles about 2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 98-88-4
benzoyl chloride

: 174149-27-0
2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-(hydroxymethyl)-6-O-benzyl-β-D-galactopyranoside

: 174149-28-1
2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Guidance literature:: With dmap; In pyridine; at 25 ℃; for 2h;
DOI:10.1021/jo951067l

Reference yield:

: 1125-88-8
benzaldehyde dimethyl acetal

: 174149-28-1
2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 89 percent / PTSA / acetonitrile / 3 h / 25 °C

2: 96 percent / DMAP / pyridine / 2 h / 25 °C

3: 93 percent / HCl/Et₂O / tetrahydrofuran / 0 °C

4: 4.50 g / P₂O₅ / dimethylformamide; dimethylsulfoxide / 2 h / 50 °C

5: 4.70 g / tetrahydrofuran / -78 °C

6: 1.) O₃, 2.) NaBH₄ / 1.) CH₂Cl₂, -78 deg C, 2.) MeOH, -78 deg C, 3 h

7: 70 percent / DMAP / pyridine / 2 h / 25 °C

With hydrogenchloride; dmap; sodium tetrahydroborate; diethyl ether; phosphorus pentoxide; toluene-4-sulfonic acid; ozone; In tetrahydrofuran; pyridine; dimethyl sulfoxide; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo951067l

Reference yield:

: 81342-44-1
(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-(trimethylsilyl)ethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate

: 174149-28-1
2-(trimethylsilyl)ethyl 2,3-di-O-benzoyl-4-C-<(benzoyloxy)methyl>-6-O-benzyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1: Amberlite IRA 910 / methanol / 2 h / 25 °C

2: 89 percent / PTSA / acetonitrile / 3 h / 25 °C

3: 96 percent / DMAP / pyridine / 2 h / 25 °C

4: 93 percent / HCl/Et₂O / tetrahydrofuran / 0 °C

5: 4.50 g / P₂O₅ / dimethylformamide; dimethylsulfoxide / 2 h / 50 °C

6: 4.70 g / tetrahydrofuran / -78 °C

7: 1.) O₃, 2.) NaBH₄ / 1.) CH₂Cl₂, -78 deg C, 2.) MeOH, -78 deg C, 3 h

8: 70 percent / DMAP / pyridine / 2 h / 25 °C

With hydrogenchloride; dmap; sodium tetrahydroborate; diethyl ether; Amberlite IRA 910; phosphorus pentoxide; toluene-4-sulfonic acid; ozone; In tetrahydrofuran; pyridine; methanol; dimethyl sulfoxide; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo951067l