N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate

Base Information

Chemical Name:N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate
CAS No.:77562-98-2
Molecular Formula:2C₂H₂O₄*C₂₀H₃₃N₃O
Molecular Weight:511.572
Hs Code.:
DSSTox Substance ID:DTXSID60998772

Synonyms:N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate;Propanamide, N-(2-(4-butyl-1-piperazinyl)-1-methylethyl)-N-phenyl-, ethanedioate (1:2);77562-98-2;DTXSID60998772;C20H33N3O.2C2H2O4;LS-119067;C20-H33-N3-O.2C2-H2-O4;Oxalic acid--N-[1-(4-butylpiperazin-1-yl)propan-2-yl]-N-phenylpropanamide (2/1)

Suppliers and Price of N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate

Chemical Property:

Vapor Pressure:2.64E-08mmHg at 25°C
Boiling Point:450.4°Cat760mmHg
Flash Point:172.8°C
Density:g/cm³
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:10
Exact Mass:511.25297977
Heavy Atom Count:36
Complexity:431

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCN1CCN(CC1)CC(C)N(C2=CC=CC=C2)C(=O)CC.C(=O)(C(=O)O)O.C(=O)(C(=O)O)O

Technology Process of N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate

There total 5 articles about N-(1-Methyl-2-(4-n-butylpiperazino)ethyl)propionanilide dioxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.2%

: 144-62-7,97993-78-7
oxalic acid

: 77562-97-1
N-<1-methyl-2-(4-n-butylpiperazino)ethyl>propionanilide

: 77562-98-2
N-[2-(4-Butyl-piperazin-1-yl)-1-methyl-ethyl]-N-phenyl-propionamide; compound with oxalic acid

Guidance literature:: In diethyl ether;
DOI:10.1248/cpb.28.3315

Reference yield:

: 5610-49-1
N-butylpiperazine

: 77562-98-2
N-[2-(4-Butyl-piperazin-1-yl)-1-methyl-ethyl]-N-phenyl-propionamide; compound with oxalic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 12.3 g / diethyl ether / 2 h / 5 °C

2: 39.3 percent / K₂CO₃ / ethanol / 8 h / Heating

3: 44.1 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 22 h / Ambient temperature

4: 96.5 percent / 3 h / 100 °C

5: 91.2 percent / diethyl ether

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1248/cpb.28.3315

Reference yield:

: 77563-19-0
2-Bromo-1-(4-butyl-piperazin-1-yl)-propan-1-one

: 77562-98-2
N-[2-(4-Butyl-piperazin-1-yl)-1-methyl-ethyl]-N-phenyl-propionamide; compound with oxalic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 39.3 percent / K₂CO₃ / ethanol / 8 h / Heating

2: 44.1 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 22 h / Ambient temperature

3: 96.5 percent / 3 h / 100 °C

4: 91.2 percent / diethyl ether

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1248/cpb.28.3315