(2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide

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Chemical Name:(2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide
CAS No.:1241494-92-7
Molecular Formula:C₂₅H₂₅F₃N₆O₂
Molecular Weight:498.508
Hs Code.:

Synonyms:(2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide

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Chemical Property of (2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide

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Technology Process of (2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide

There total 1 articles about (2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1123340-53-3
(2E)-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide

: 1241494-80-3
(2S)-5-oxo-2-[2-(trifluoromethyl)phenyl]pentanenitrile

: 1241494-92-7
(2E)-N'-{(4S)-4-cyano-4-[2-(trifluoromethyl)phenyl]butyl}-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide

Guidance literature:: (2E)-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylohydrazide; (2S)-5-oxo-2-[2-(trifluoromethyl)phenyl]pentanenitrile; With toluene-4-sulfonic acid; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 20 ℃; Cooling with ice;

With sodium hydrogencarbonate; In tetrahydrofuran; water; ethyl acetate;