rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide

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Chemical Name:rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide
CAS No.:1397683-23-6
Molecular Formula:C₁₉H₁₄F₄N₆O
Molecular Weight:418.353
Hs Code.:

Synonyms:rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide

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Chemical Property of rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide

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Technology Process of rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide

There total 1 articles about rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 107504-08-5
5-fluoropicolinic acid

: 1397683-78-1
rac-6-(5-amino-2-fluoro-phenyl)-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-4-ylamine

: 1397683-23-6
rac-5-fluoro-pyridine-2-carboxylic acid[3-(4-amino-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl)-4-fluoro-phenyl]-amide

Guidance literature:: 5-fluoropicolinic acid; With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; at 20 ℃; for 0.0833333h;

rac-6-(5-amino-2-fluoro-phenyl)-6-difluoromethyl-6,7-dihydro-pyrazolo[1,5-a]pyrazin-4-ylamine; In methanol; at 0 - 20 ℃; for 1h;

With sodium carbonate; In methanol; water;