1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide

Base Information

Chemical Name:1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide
CAS No.:1104937-78-1
Molecular Formula:C₂₂H₂₅FN₄O
Molecular Weight:380.465
Hs Code.:

Synonyms:1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide

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Chemical Property of 1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide

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Technology Process of 1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide

There total 1 articles about 1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 372-19-0
meta-fluoroaniline

: 1104938-15-9
1-(2-chloro-ethyl)-piperidine-4-carboxylic acid 4-cyano-benzylamide hydrochloride

: 1104937-78-1
1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; sodium iodide; In acetonitrile; at 100 ℃; for 0.166667h; Microwave irradiation;

Reference yield:

: 1104937-78-1
1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide

: 149104-88-1
4-methanesulphonylphenylboronic acid

: 1104937-28-1
1-{2-[(3-fluoro-phenyl)-(4-methanesulfonyl-phenyl)-amino]-ethyl}-piperidine-4-carboxylic acid 4-cyano-benzylamide

Guidance literature:: 4-methanesulphonylphenylboronic acid; With copper diacetate; In dichloromethane; water; at 20 ℃; for 0.0833333h; Molecular sieve;

1-[2-(3-fluoro-phenylamino)-ethyl]-piperidine-4-carboxylic acid 4-cyano-benzylamide; With oxygen; In dichloromethane; water; for 24h;