3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Base Information

Chemical Name:3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol
CAS No.:668468-59-5
Molecular Formula:C₁₂H₁₃Cl₂N₃OS
Molecular Weight:318.227
Hs Code.:

Synonyms:3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Suppliers and Price of 3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

There total 4 articles about 3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 3-(4-(2,4-dichlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-yl)propan-1-ol

: 74-88-4
methyl iodide

: 668468-59-5
3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Guidance literature:: With potassium carbonate; In acetonitrile; at 20 ℃; for 12h;
DOI:10.1021/acs.jmedchem.9b02128

Reference yield:

: 554-00-7,51908-09-9
2,4-Dichloroaniline

: 668468-59-5
3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium carbonate / chloroform / Cooling with ice

1.2: 2 h / Cooling with ice

2.1: ethanol / 10 h / Reflux

3.1: sodium hydroxide / water / 10 h / Reflux

3.2: 0.17 h

4.1: potassium carbonate / acetonitrile / 12 h / 20 °C

With sodium carbonate; potassium carbonate; sodium hydroxide; In ethanol; chloroform; water; acetonitrile;
DOI:10.1021/acs.jmedchem.9b02128

Reference yield:

: 6590-96-1
2, 4-dichlorophenyl isothiocyanate

: 668468-59-5
3-(4-(2,4-dichlorophenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)propan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / 10 h / Reflux

2.1: sodium hydroxide / water / 10 h / Reflux

2.2: 0.17 h

3.1: potassium carbonate / acetonitrile / 12 h / 20 °C

With potassium carbonate; sodium hydroxide; In ethanol; water; acetonitrile;
DOI:10.1021/acs.jmedchem.9b02128