methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate

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Chemical Name:methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate
CAS No.:203311-03-9
Molecular Formula:C₂₄H₂₈FN₃O₉
Molecular Weight:521.499
Hs Code.:

Synonyms:methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate

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Chemical Property of methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate

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Technology Process of methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate

There total 2 articles about methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 173775-54-7
(R)-N-(tert-butoxycarbonyl)-4-fluoro-3-nitrophenylalanine

: (S)-2-Amino-3-(3,4-bis-trimethylsilanyloxy-phenyl)-propionic acid methyl ester

: 203311-03-9
methyl N-[N-(tert-butyloxycarbonyl)-L-(3,4-dihydroxyphenylalanyl)]-D-4-fluoro-3-nitrophenylalaninate

Guidance literature:: (R)-N-(tert-butoxycarbonyl)-4-fluoro-3-nitrophenylalanine; (S)-2-Amino-3-(3,4-bis-trimethylsilanyloxy-phenyl)-propionic acid methyl ester; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.5h;

With hydrogenchloride; In water;
DOI:10.1021/jo990432w