(1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate

Base Information

• Chemical Name: (1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate
• CAS No.: 1225621-04-4
• Molecular Formula: C₂₃H₃₃NO₈S
• Molecular Weight: 483.583
• Mol file: 1225621-04-4.mol

Synonyms:(1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate

Chemical Property of (1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate

There total 1 articles about (1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C22H31NO6 (1225621-03-3) + methanesulfonyl chloride (124-63-0) → (1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate (1225621-04-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1055/S-0029-1218603

Reference yield: 90.0%

(1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-(methoxymethoxy)-4-methyl-5-hexenyl methanesulfonate (1225621-04-4) → (1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-hydroxy-4-methyl-5-hexenyl methanesulfonate (1225621-07-7)

Guidance literature:

With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 1h; chemoselective reaction; Inert atmosphere;

DOI:10.1055/S-0029-1218603

upstream raw materials:

C₂₂H₃₁NO₆

methanesulfonyl chloride

Downstream raw materials:

(1R,4R)-1-(1S)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolan-3-yl]-1-methyl-2-oxoethyl-4-hydroxy-4-methyl-5-hexenyl methanesulfonate