Chemical Property of Fleroxacin
Chemical Property:
- Appearance/Colour:white needle-like crystals
- Vapor Pressure:2.73E-12mmHg at 25°C
- Melting Point:264-266 °C
- Refractive Index:1.568
- Boiling Point:535.3 °C at 760 mmHg
- PKA:-0.54±0.20(Predicted)
- Flash Point:277.6 °C
- PSA：65.78000
- Density:1.409 g/cm3
- LogP:1.70210
- Storage Temp.:2-8°C
- Solubility.:0.1 M NaOH: soluble10mg/mL
- XLogP3:-0.1
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:9
- Rotatable Bond Count:4
- Exact Mass:369.13002593
- Heavy Atom Count:26
- Complexity:595
- Purity/Quality:
-
99%, *data from raw suppliers
Fleroxacin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F
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Description
Fleroxacin is a new, once daily trifluoroquinolone antibacterial structurally related to
norfloxacin. Available in both oral and IV formulations, it is reportedly useful in the
treatment of gonorrhea, bacterial enteritis, chronic bronchitis and urinary tract
infections. Fleroxacin has a longer serum half-life (9-12 hours) than other drugs of this
class, such as ciprofloxacin, enoxacin and norfloxacin.
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Uses
antibiotic
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Therapeutic Function
Antibacterial
