3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole

Base Information

• Chemical Name: 3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole
• CAS No.: 311779-90-5
• Molecular Formula: C₂₃H₁₉FN₄O₂
• Molecular Weight: 402.428

Synonyms:3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole

Chemical Property of 3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole

There total 1 articles about 3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H14N2O6 + 1-(4-fluorophenyl)-2-(pyridin-4-yl)-2-ethanone (115858-98-5) → 3(5)-(4-fluorophenyl)-5(3)-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole (311779-90-5)

Guidance literature:

Reference yield: 44.0%

3(5)-(4-fluorophenyl)-5(3)-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole (311779-90-5) + methyl iodide (74-88-4) → 3-(4-fluorophenyl)-1-methyl-5-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole

Guidance literature:

3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at -70 - 20 ℃; for 1.5h;

Reference yield:

3(5)-(4-fluorophenyl)-5(3)-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole (311779-90-5) → 5-[3-(4-Aminophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazole

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 1 h / 20 °C

1.2: 1.5 h / -70 - 20 °C

2.1: palladium 10% on activated carbon; cyclohexene / methanol / 2 h / Heating / reflux

With palladium 10% on activated carbon; sodium hydride; cyclohexene; In tetrahydrofuran; methanol;

upstream raw materials:

1-(4-fluorophenyl)-2-(pyridin-4-yl)-2-ethanone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 311779-90-5 3⁽⁵⁾-(4-fluorophenyl)-5⁽³⁾-[3-(4-nitrophenyl)propyl]-4-(4-pyridyl)pyrazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send