ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Base Information

Chemical Name:ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate
CAS No.:152499-73-5
Molecular Formula:C₁₅H₁₈N₂O₄
Molecular Weight:290.319
Hs Code.:

Synonyms:ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Suppliers and Price of ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

There total 4 articles about ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 152499-74-6
ethyl (RS)-2-(N-benzyloxycarbonyl-N'-tert-butoxycarbonylhydrazino)-5,5-(1,3-propanediyldioxy)pentanoate

: 152499-73-5
ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Guidance literature:: With trifluoroacetic acid; for 1h; Ambient temperature;
DOI:10.1055/s-1993-25947

Reference yield:

: 145022-63-5
ethyl 5,5-(1,3-propanediyldioxy)-2-oxopentanoate

: 152499-73-5
ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 58 percent / hexane / 3 h / Heating

2: 98 percent / NaCNBH₃ / acetonitrile; acetic acid / 24 h

3: 74 percent / 1N NaHCO₃ / dioxane; H₂O / 16 h / Ambient temperature

4: 63 percent / CF₃CO₂H / 1 h / Ambient temperature

With sodium cyanoborohydride; sodium hydrogencarbonate; trifluoroacetic acid; In 1,4-dioxane; hexane; water; acetic acid; acetonitrile;
DOI:10.1055/s-1993-25947

Reference yield:

: ethyl (E/Z)-2-(tert-butoxycarbonylhydrazono)-5,5-(1,3-propanediyldioxy)pentanoate

: 152499-73-5
ethyl (3RS)-2-benzyloxycarbonyl-2,3,4,5-tetrahydro-3-pyridazinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / NaCNBH₃ / acetonitrile; acetic acid / 24 h

2: 74 percent / 1N NaHCO₃ / dioxane; H₂O / 16 h / Ambient temperature

3: 63 percent / CF₃CO₂H / 1 h / Ambient temperature

With sodium cyanoborohydride; sodium hydrogencarbonate; trifluoroacetic acid; In 1,4-dioxane; water; acetic acid; acetonitrile;
DOI:10.1055/s-1993-25947