(S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol

Base Information

• Chemical Name: (S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol
• CAS No.: 1128025-29-5
• Molecular Formula: C₃₁H₄₂O₃Si
• Molecular Weight: 490.758
• Mol file: 1128025-29-5.mol

Synonyms:(S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol

Chemical Property of (S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol

There total 1 articles about (S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(S)-8-(benzyloxy)octane-1,2-diol (1128025-17-1) + tert-butylchlorodiphenylsilane (58479-61-1) → (S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol (1128025-29-5)

Guidance literature:

With 1H-imidazole; dmap; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1002/ejoc.200800680

Reference yield: 91.0%

(S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-ol (1128025-29-5) + methanesulfonyl chloride (124-63-0) → (S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-yl methanesulfonate (1128025-30-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1002/ejoc.200800680

upstream raw materials:

(S)-8-(benzyloxy)octane-1,2-diol

tert-butylchlorodiphenylsilane

Downstream raw materials:

(S)-8-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)octan-2-yl methanesulfonate