1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

Base Information

Chemical Name:1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide
CAS No.:865713-02-6
Molecular Formula:C₁₉H₂₄ClN₃O₃
Molecular Weight:377.871
Hs Code.:

Synonyms:1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

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Chemical Property of 1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

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Technology Process of 1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

There total 2 articles about 1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 639067-82-6
1-(cyclohexylmethyl)-7-methoxyindole-3-carbonyl chloride

: 30956-28-6
2-chloroacetic acid hydrazide

: 865713-02-6
1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield:

: 639067-82-6
1-(cyclohexylmethyl)-7-methoxyindole-3-carbonyl chloride

: 868-83-7
2-chloroacetohydrazide hydrochloride

: 865713-02-6
1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2010.10.093

Reference yield: 71.0%

: 865713-02-6
1-cyclohexylmethyl-7-methoxy-1H-indole-3-carboxylic acid N'-(2-chloroacetyl)hydrazide

: 865713-03-7
3-(5-chloromethyl-[1,3,4]oxadiazol-2-yl)-1-cyclohexylmethyl-7-methoxy-1H-indole

Guidance literature:: With N-(triethylammoniumsulfonyl)carbamate; In tetrahydrofuran; at 150 ℃; Microwave irradiation;
DOI:10.1016/j.bmcl.2010.10.093